Sleep Medicine
Volume 1, Issue 2 , Pages 91-99, 1 April 2000

Valerian for insomnia: a systematic review of randomized clinical trials

Department of Complementary Medicine, School of Postgraduate Medicine and Health Sciences, University of Exeter, 25 Victoria Park Road, Exeter EX2 4NT, UK

Received 15 October 1999; received in revised form 26 November 1999; accepted 26 November 1999.

Abstract 

Objective: To systematically review the evidence for the effects of the herb valerian (Valeriana officinalis) on insomnia, based on randomized, placebo-controlled, double-blind trials.

Background: Valerian has long been advocated and used for promoting sleep but until quite recently evidence was solely anecdotal. However, during the last two decades a number of clinical trials have been conducted.

Materials and methods: Systematic literature searches were performed to locate randomized, placebo-controlled, double-blind trials measuring the effect of valerian monopreparations on sleep in human participants. Data were extracted in a standardized manner and methodological quality was assessed by the Jadad score.

Results: Nine trials were located meeting the selection criteria. The findings of the studies were contradictory and there was great inconsistency between trials in terms of patients, experimental design and procedures and methodological quality.

Conclusion: The evidence for valerian as a treatment for insomnia is inconclusive. There is a need for rigorous trials to determine its efficacy.

Keywords: Insomnia, Sleep disorders, Valerian, Herbal medicine, Randomized controlled trials

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PII: S1389-9457(99)00015-5

Sleep Medicine
Volume 1, Issue 2 , Pages 91-99, 1 April 2000