Sleep induced abnormal motor behaviors caused by medium-chain acyl-CoA dehydrogenase deficiency: A case report

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Video “episode recorded in hospital”: including two parts. The video “episode in hospital 1” recorded during her sleep shown that the main episodic manifestations of the patient were trunk twisting and the lower limbs treading. The EEG combined with the video shown that the episodes happened during stage II of NREM sleep, the motor episodes of the patient did not interrupt NREM sleep. We could see the spindles and slow waves appearing before, during and after episodes clearly. The video “Episode in hospital 2” shown that the patient was recumbent on the right side and her main episodic manifestations were trunk torsion, twisting, lower limbs treading, shaking and circling in the air and position changing. We woke her up by patting her during episode and stopped her attack. Because there was something wrong with the microphone when her doing PSG, we couldn’t hear her guttural sounds. The PSG combined with it was shown in the supplement of Fig. B.

Video “episode recorded at home”: it including 3 videos shown that the episodes happened during sleep were associated with various complex motor behaviors with uttering guttural sounds mainly including trunk torsion, shaking and turning over, limbs choreic movement, legs treading and circling in the air and position changing.