Sleep Medicine
Volume 11, Issue 8 , Pages 759-765 , September 2010

Double-blind, randomized, placebo controlled trial on the effect of 10 days low-frequency rTMS over the vertex on sleep in Parkinson’s disease

  • Pablo Arias

      Affiliations

    • Neuroscience and Motor Control Group (NEUROcom), Department of Medicine-INEF and Institute for Biomedical Research (INIBIC), University of A Coruña, Spain
    • ,
  • Jamile Vivas

      Affiliations

    • Neuroscience and Motor Control Group (NEUROcom), Department of Medicine-INEF and Institute for Biomedical Research (INIBIC), University of A Coruña, Spain
    • ,
  • Kenneth L. Grieve

      Affiliations

    • Neuroscience and Motor Control Group (NEUROcom), Department of Medicine-INEF and Institute for Biomedical Research (INIBIC), University of A Coruña, Spain
    • Faculty of Life Sciences, The University of Manchester, UK
    • ,
  • Javier Cudeiro

      Affiliations

    • Neuroscience and Motor Control Group (NEUROcom), Department of Medicine-INEF and Institute for Biomedical Research (INIBIC), University of A Coruña, Spain
    • Corresponding Author InformationCorresponding author. Address: Neuroscience and Motor Control Group (NEUROcom), Department of Medicine-INEF and Institute for Biomedical Research (INIBIC), University of A Coruña, 15006 Coruna, Spain. Tel.: +34 981 167000x5859; fax: +34 981 167155.

Received 8 April 2010 ,Revised 18 May 2010 ,Accepted 19 May 2010.

References 

  1. Jankovic J. Parkinson’s disease: clinical features and diagnosis. J Neurol Neurosurg Psychiatry. 2008;79:368–376
  2. Askenasy JJ. Sleep disturbances in Parkinsonism. J Neural Transm. 2003;110:125–150
  3. Partinen M. Sleep disorder related to Parkinson’s disease. J Neurol. 1997;244:S3–S6
  4. Chaudhuri KR, Healy DG, Schapira AHV. Non-motor symptoms of Parkinson’s disease: diagnosis and management. Lancet Neurol. 2006;5:235–245
  5. Young A, Horne M, Churchward T, Freezer N, Holmes P, Ho M. Comparison of sleep disturbance in mild versus severe Parkinson’s disease. Sleep. 2002;25:573–577
  6. Menza MA, Rosen RC. Sleep in Parkinsons-disease – the role of depression and anxiety. Psychosomatics. 1995;36:272–276
  7. Comella CL. Sleep disorders in Parkinson’s disease: an overview. Mov Disord. 2007;22:S367–S373
  8. Tandberg E, Larsen JP, Karlsen K. A community-based study of sleep disorders in patients with Parkinson’s disease. Mov Disord. 1998;13:895–899
  9. Comella CL, Morrissey M, Janko K. Nocturnal activity with nighttime pergolide in Parkinson disease: a controlled study using actigraphy. Neurology. 2005;64:1450–1451
  10. Chaudhuri KR, Schapira AHV. Non-motor symptoms of Parkinson’s disease: dopaminergic pathophysiology and treatment. Lancet Neurol. 2009;8:464–474
  11. Askenasy JJM, Yahr MD. Reversal of sleep disturbance in Parkinsons-disease by antiparkinsonian therapy – a preliminary-study. Neurology. 1985;35:527–532
  12. Stocchi F, Barbato L, Nordera G, Berardelli A, Ruggieri S. Sleep disorders in Parkinson’s disease. J Neurol. 1998;245:S15–S18
  13. Hallett M. Transcranial magnetic stimulation: a primer. Neuron. 2007;55:187–199
  14. Wassermann EM, Lisanby SH. Therapeutic application of repetitive transcranial magnetic stimulation: a review. Clin Neurophysiol. 2001;112:1367–1377
  15. Edwards MJ, Talelli P, Rothwell JC. Clinical applications of transcranial magnetic stimulation in patients with movement disorders. Lancet Neurol. 2008;7:827–840
  16. Valero-Cabré A, Payne BR, Pascual-Leone A. Opposite impact on (14)C-2-deoxyglucose brain metabolism following patterns of high and low frequency repetitive transcranial magnetic stimulation in the posterior parietal cortex. Exp Brain Res. 2007;176:603–615
  17. Di Lazzaro V, Oliviero A, Pilato F, Saturno E, Insola A, Mazzone P, et al. Descending volleys evoked by transcranial magnetic stimulation of the brain in conscious humans: effects of coil shape. Clin Neurophysiol. 2002;113(1):114–119
  18. Di Lazzaro V, Oliviero A, Mazzone P, Insola A, Pilato F, Saturno E, et al. Comparison of descending volleys evoked by monophasic and biphasic magnetic stimulation of the motor cortex in conscious humans. Exp Brain Res. 2001;141:121–127
  19. Sommer M, Alfaro A, Rummel M, Speck S, Lang N, Tings T, et al. Half sine, monophasic and biphasic transcranial magnetic stimulation of the human motor cortex. Clin Neurophysiol. 2006;117(4):838–844
  20. Di Lazzaro V, Oliviero A, Saturno E, Pilato F, Insola A, Mazzone P, et al. The effect on corticospinal volleys of reversing the direction of current induced in the motor cortex by transcranial magnetic stimulation. Exp Brain Res. 2001;138(2):268–273
  21. van Dijk KD, Most EIS, van Someren EJW, Berendse HW, van der Werf YD. Beneficial effect of transcranial magnetic stimulation on sleep in Parkinson’s disease. Mov Disord. 2009;24:878–884
  22. Huber R, Esser SK, Ferrarelli F, Massimini M, Peterson MJ, Tononi G. TMS-induced cortical potentiation during wakefulness locally increases slow wave activity during sleep. PLoS One. 2007;2(3):e276
  23. Brunner H, Wetter TC, Hogl B, Yassouridis A, Trenkwalder C, Friess E. Microstructure of the non-rapid eye movement sleep electroencephalogram in patients with newly diagnosed Parkinson’s disease: effects of dopaminergic treatment. Mov Disord. 2002;17:928–933
  24. Massimini M, Ferrarelli F, Esser SK, Riedner BA, Huber R, Murphy M, et al. Triggering sleep slow waves by transcranial magnetic stimulation. Proc Natl Acad Sci USA. 2007;104(20):8496–8501
  25. Mally J, Stone TW. Improvement in Parkinsonian symptoms after repetitive transcranial magnetic stimulation. J Neurol Sci. 1999;162(2):179–184
  26. Mally J, Stone TW. Therapeutic and ‘‘dose-dependent’’ effect of repetitive microelectroshock induced by transcranial magnetic stimulation in Parkinson’s disease. J Neurosci Res. 1999;57(6):935–940
  27. Lomarev MP, Kanchana S, Bara-Jimenez W, Iyer M, Wassermann EM, Hallett M. Placebo-controlled study of rTMS for the treatment of Parkinson’s disease. Mov Disord. 2006;21:325–331
  28. Sadeh A, Hauri PJ, Kripke DF, Lavie P. The role of actigraphy in the evaluation of sleep disorders. Sleep. 1995;18:288–302
  29. Kushida CA, Chang A, Gadkary C, Guilleminault C, Carrillo O, Dement WC. Comparison of actigraphic, polysomnographic, and subjective assessment of sleep parameters in sleep-disordered patients. Sleep Med. 2001;2:389–396
  30. van Hilten B, Hoff JI, Middelkoop HA, van der Velde EA, Kerkhof GA, Wauquier A, et al. Sleep disruption in Parkinson’s disease. Assessment by continuous activity monitoring. Arch Neurol. 1994;51:922–928
  31. Chaudhuri KR, Pal S, DiMarco A, Whately-Smith C, Bridgman K, Mathew R, et al. The Parkinson’s disease sleep scale: a new instrument for assessing sleep and nocturnal disability in Parkinson’s disease. J Neurol Neurosurg Psychiatry. 2002;73:629–635
  32. Chaudhuri KR, Martinez-Martin P. Clinical assessment of nocturnal disability in Parkinson’s disease – the Parkinson’s disease sleep scale. Neurology. 2004;63:S17–S20
  33. Martinez-Martin P, Salvador C, Menéndez-Guisasola L, González S, Tobías A, Almazán J, et al. Parkinson’s disease sleep scale: validation study of a Spanish version. Mov Disord. 2004;19:1227–1232
  34. Perez-Lloret S, Rossi M, Nouzeilles MI, Trenkwalder C, Cardinali DP, Merello M. Parkinson’s disease sleep scale, sleep logs, and actigraphy in the evaluation of sleep in Parkinsonian patients. J Neurol. 2009;256:1480–1484
  35. Hamilton M. A rating scale for depression. J Neurol Neurosurg Psychiatry. 1960;23:56–62
  36. Ramos-Brieva JA, Cordero-Villafafila A. A new validation of the Hamilton rating scale for depression. J Psychiatr Res. 1988;22:21–28
  37. Okabe S, Ugawa Y, Kanazawa I. Effectiveness of rTMS on Parkinson’s disease study group. 0.2-Hz repetitive transcranial magnetic stimulation has no add-on effects as compared to a realistic sham stimulation in Parkinson’s disease. Mov Disord. 2003;18:382–388

PII: S1389-9457(10)00244-3

doi: 10.1016/j.sleep.2010.05.003

Sleep Medicine
Volume 11, Issue 8 , Pages 759-765 , September 2010

Article Tools

* Image Usage & Resolution