Sleep Medicine
Volume 11, Issue 1 , Pages 75-81 , January 2010

Changes of cortical excitability after dopaminergic treatment in restless legs syndrome

  • Anna Scalise

      Affiliations

    • Department of Neurosciences, S. Maria della Misericordia University-Hospital, Udine, Italy
    • Corresponding Author InformationCorresponding author. Address: Department of Neurosciences, S. Maria della Misericordia Hospital, P.le S. Maria della Misericordia 15, 33100 Udine, Italy. Tel.: +39 0432552565; fax: +39 0432552719.
    • ,
  • Italo Pittaro-Cadore

      Affiliations

    • Department of Neurosciences, S. Maria della Misericordia University-Hospital, Udine, Italy
    • ,
  • Francesco Janes

      Affiliations

    • DPRSC, University of Udine, Italy
    • ,
  • Roberto Marinig

      Affiliations

    • Department of Neurosciences, S. Maria della Misericordia University-Hospital, Udine, Italy
    • ,
  • Gian Luigi Gigli

      Affiliations

    • DPRSC, University of Udine, Italy

Received 7 January 2009 ,Revised 27 April 2009 ,Accepted 1 May 2009.

References 

  1. Hening W. The clinical neurophysiology of the restless legs syndrome and periodic limb movements. Part I: Diagnosis, assessment, and characterization. Clin Neurophysiol. 2004;115:1965–1974
  2. Allen RP, Picchietti D, Hening WA, Trenkwalder C, Walters AS, Montplaisir J. Restless legs syndrome: diagnostic criteria, special considerations, and epidemiology. A report from the restless legs syndrome diagnosis and epidemiology workshop at the National Institutes of Health. Sleep Med. 2003;4:101–119
  3. Trenkwalder C, Paulus W. Why do restless legs occur at rest? Pathophysiology of neuronal structures in RLS. Neurophysiology of RLS (part 2). Clin Neurophysiol. 2004;115:1975–1988
  4. Allen R. Dopamine and iron in the pathophysiology of restless legs syndrome (RLS). Sleep Med. 2004;5:385–391
  5. Hilker R, Burghaus L, Razai N, Jacobs AH, Szelies B, Heiss WD. Functional brain imaging in combined motor and sleep disorders. J Neurol Sci. 2006;248(1–2):223–226[Epub 2006 June 5, Review]
  6. Wetter TC, Eisensehr I, Trenkwalder C. Functional neuroimaging studies in restless legs syndrome. Sleep Med. 2004;5(4):401–406[Review]
  7. Samii A, Wassermann EM, Ikoma K, Mercuri B, Hallett M. Characterization of postexercise facilitation and depression of motor evoked potentials to transcranial magnetic stimulation. Neurology. 1996;46:1376–1382
  8. Sacco P, Thickbroom GW, Thompson ML, Mastaglia F. Changes in corticomotor excitation and inhibition during prolonged submaximal muscle contractions. Muscle Nerve. 1997;20:1158–1166
  9. Caramia MD, Scalise A, Gordon R, Michalewski HJ, Starr A. Delayed facilitation of motor cortex excitability following repetitive finger movements. Clin Neurophysiol. 2000;111:1654–1660
  10. Starr A, Scalise A, Gordon R, Michalewski HJ, Caramia MD. Motor cortex excitability in chronic fatigue syndrome. Clin Neurophysiol. 2000;111:2025–2031
  11. Kujirai T, Caramia MD, Rothwell JC, et al. Corticortical inhibition in human motor cortex. J Physiol (London). 1993;471:501–519
  12. Currà A, Modugno N, Inghilleri M, Manfredi M, Hallett M, Berardelli A. Transcranial magnetic stimulation techniques in clinical investigation. Neurology. 2002;59:1851–1859
  13. Rossini PM, Barker AT, Berardelli A, et al. Non-invasive electrical and magnetic stimulation of the brain, spinal cord and roots: basic principles and procedures for routine clinical application. Report of an IFCN committee. Electroencephalogr Clin Neurophysiol. 1994;91:79–92
  14. Stetkarova I, Leis AA, Stokic DS, Delapasse JS, Tarkka IM. Characteristics of silent period after transcranial magnetic stimulation. Am J Phys Med Rehabil. 1994;73:98–102
  15. Entezari-Taher M, Singleton JR, Jones CR, Meekins G, Petajan JH, Smith AG. Change in excitability of motor cortical circuitry in primary restless legs syndrome. Neurology. 1999;53:1201–1205
  16. Tergau F, Wischer S, Paulus W. Motor system excitability in patients with restless legs syndrome. Neurology. 1999;52:1060
  17. Quatrale R, Manconi M, Gastaldo E, et al. Neurophysiological study of corticomotor pathways in restless legs syndrome. Clin Neurophysiol. 2003;114:1638–1645
  18. Stiasny-Kolster K, Haeske H, Tergau F, Muller HH, Braune HJ, Oertel WH. Cortical silent period is shortened in restless legs syndrome independently from circadian rhythm. Suppl Clin Neurophysiol. 2003;56:381–389
  19. Scalise A, Pittaro-Cadore I, Golob EJ, Gigli GL. Absence of postexercise and delayed facilitation of motor cortex excitability in restless legs syndrome: evidence of altered cortical plasticity?. Sleep. 2006;29(6):770–775
  20. Scalise A, Pittaro-Cadore I, Gigli GL. Motor cortex excitability in restless legs syndrome. Sleep Med. 2004;5:393–396
  21. Priori A, Oliviero A, Donati E, Callea L, Bertolasi L, Rothwell JC. Human handedness and asymmetry of the motor cortical silent period. Exp Brain Res. 1999;128:390–396
  22. Keller A, Pavlides C, Asanuma H. Long-term potentiation in the cat somatosensory cortex. NeuroReport. 1990;1:49–52
  23. Ghirardi M, Montarolo PG, Kandel ER. A novel intermediate stage in the transition between short- and long-term facilitation in the sensory to motor neuron synapse of aplasia. Neuron. 1995;20:413–420
  24. Asanuma H, Pavlides C. Neurobiological basis of motor learning in mammals. NeuroReport. 1997;38:1–6
  25. Benke TA, Luthi A, Isaac JT, Collingridge GL. Modulation of AMPA receptor unitary conductance by synaptic activity. Nature. 1998;393:793–797
  26. Buonomano DV, Merzenich MM. Cortical plasticity: from synapses to maps. Annu Rev Neurosci. 1998;21:149–186
  27. Ziemann U, Meintzschel F, Korchounov A, Ilic TV. Pharmacological modulation of plasticity in the human motor cortex. Neurorehabil Neural Repair. 2006;20(2):243–251[Review]
  28. Cooke SF, Bliss TV. Plasticity in the human central nervous system. Brain. 2006;129(Pt 7):1659–1673[Epub 2006 May 3, Review]
  29. Ziemann U, Ilic TV, Jung P. Long-term potentiation (LTP)-like plasticity and learning in human motor cortex – investigations with transcranial magnetic stimulation (TMS). Suppl Clin Neurophysiol. 2006;59:19–25
  30. Huang YZ, Edwards MJ, Rounis E, Bhatia KP, Rothwell JC. Theta burst stimulation of the human motor cortex. Neuron. 2005;45(2):201–206
  31. Nardone R, Ausserer H, Bratti A, et al. Cabergoline reverses cortical hyperexcitability in patients with restless legs syndrome. Acta Neurol Scand. 2006;114(4):244–249
  32. Kutukcu Y, Dogruer E, Yetkin S, Ozgen F, Vural O, Aydin H. Evaluation of periodic leg movements and associated transcranial magnetic stimulation parameters in restless legs syndrome. Muscle Nerve. 2006;33(1):133–137
  33. Gosler A, Liepert J. Influence of Carbergoline on motor excitability in patients with restless legs syndrome. J Clin Neurophysiol. 2007;24:456–460
  34. Priori A, Berardelli A, Inghilleri M, Accornero N, Manfredi M. Motor cortical inhibition and the dopaminergic system. Pharmacological changes in the silent period after transcranial brain stimulation in normal subjects, patients with Parkinson’s disease and drug-induced parkinsonism. Brain. 1994;117:317–323
  35. Ridding MC, Inzelberg R, Rothwell JC. Changes in excitability of the motor cortical circuitry in patients with Parkinson’s disease. Ann Neurol. 1995;37:181–188
  36. Rijsman RM, Stam CJ, de Weerd AW. Abnormal H-reflexes in periodic limb movement disorder; impact on understanding the pathophysiology of the disorder. Clin Neurophysiol. 2005;116(1):204–210
  37. Centonze D, Picconi B, Gubellini P, Bernardi G, Calabresi P. Dopaminergic control of synaptic plasticity in the dorsal striatum. Eur J Neurosci. 2001;13:1071–1077
  38. Bruel-Jungerman E, Davis S, Laroche S. Brain plasticity mechanisms and memory: a party of four. Neuroscientist. 2007;13(5):492–505[Review]
  39. Flöel A, Breitenstein C, Hummel F, Celnik P, Gingert C, Sawaki L, et al. Dopaminergic influences on formation of a motor memory. Ann Neurol. 2005;58(1):121–130
  40. Jay TM. Dopamine: a potential substrate for synaptic plasticity and memory mechanisms. Prog Neurobiol. 2003;69(6):375–390[Review]
  41. Kuo MF, Paulus W, Nitsche MA. Boosting focally-induced brain plasticity by dopamine. Cereb Cortex. 2008;18(3):648–651
  42. Calabresi P, Picconi P, Parnetti L, Di Filippo M. A convergent model for cognitive dysfunctions in Parkinson’s disease: the critical dopamine-acetylcholine synaptic balance. Lancet Neurol. 2006;5(11):974–983[Review]
  43. Pascual-Leone A, Valls-Sole J, Brasil-Neto JP, Cammarota A, Grafman J, Hallett M. Akinesia in Parkinson’s disease. II. Effects of subthreshold repetitive transcranial motor cortex stimulation. Neurology. 1994;44(5):892–898
  44. Ueki Y, Mima T, Kotb MA, et al. Altered plasticity of the human motor cortex in Parkinson’s disease. Ann Neurol. 2006;59(1):60–71
  45. Meintzschel F, Ziemann U. Modification of practice-dependent plasticity in human motor cortex by neuromodulators. Cereb Cortex. 2006;16(8):1106–1115[Epub 2005 October 12]

PII: S1389-9457(09)00222-6

doi: 10.1016/j.sleep.2009.05.003

Sleep Medicine
Volume 11, Issue 1 , Pages 75-81 , January 2010

Article Tools

* Image Usage & Resolution