Sleep Medicine
Volume 10, Issue 9 , Pages 1059-1062 , October 2009

A brainstem inflammatory lesion causing REM sleep behavior disorder and sleepwalking (parasomnia overlap disorder)

  • Nadège Limousin

      Affiliations

    • Unité des pathologies du sommeil, Inserm UMR975 and Pierre and Marie Curie University, Hopital Pitié-Salpetrière, APHP, 47-83 boulevard de l’Hôpital, 75651 Paris Cedex 13, France
    • ,
  • Caroline Dehais

      Affiliations

    • Service de neurologie, fondation ophtalmologique Adolphe-de-Rotschild, Paris, France
    • ,
  • Olivier Gout

      Affiliations

    • Service de neurologie, fondation ophtalmologique Adolphe-de-Rotschild, Paris, France
    • ,
  • Françoise Héran

      Affiliations

    • Service de neurologie, fondation ophtalmologique Adolphe-de-Rotschild, Paris, France
    • ,
  • Delphine Oudiette

      Affiliations

    • Unité des pathologies du sommeil, Inserm UMR975 and Pierre and Marie Curie University, Hopital Pitié-Salpetrière, APHP, 47-83 boulevard de l’Hôpital, 75651 Paris Cedex 13, France
    • ,
  • Isabelle Arnulf

      Affiliations

    • Unité des pathologies du sommeil, Inserm UMR975 and Pierre and Marie Curie University, Hopital Pitié-Salpetrière, APHP, 47-83 boulevard de l’Hôpital, 75651 Paris Cedex 13, France
    • Corresponding Author InformationCorresponding author. Tel.: +33 1 42 16 77 02; fax: +33 1 42 16 77 00.

Received 30 October 2008 ,Revised 14 December 2008 ,Accepted 23 December 2008.

References 

  1. American Academy of Sleep Medicine. The International Classification of Sleep Disorders – Revised. Chicago, IL: 2005.
  2. Boeve BF, Silber MH, Saper CB, et al. Pathophysiology of REM sleep behaviour disorder and relevance to neurodegenerative disease. Brain. 2007;130:2770–2788
  3. Schenck CH, Boyd JL, Mahowald MW. A parasomnia overlap disorder involving sleepwalking, sleep terrors, and REM sleep behavior disorder in 33 polysomnographically confirmed cases. Sleep. 1997;20:972–981
  4. Kimura K, Tachibana N, Kohyama J, Otsuka Y, Fukazawa S, Waki R. A discrete pontine ischemic lesion could cause REM sleep behavior disorder. Neurology. 2000;26(55):894–895
  5. Plazzi G, Montagna P. Remitting REM Sleep behavior disorder as the initial sign of multiple sclerosis. Sleep Med. 2002;3:437–439
  6. Zambelis T, Paparrigopoulos T, Soldatos CR. REM sleep behaviour disorder associated with a neurinoma of the left pontocerebellar angle. J Neurol Neurosurg Psychiatry. 2002;72:821–822
  7. Tippmann-Peikert M, Boeve BF, Keegan BM. REM sleep behavior disorder initiated by acute brainstem multiple sclerosis. Neurology. 2006;66:1277–1279
  8. Iranzo A, Aparicio J. A lesson from anatomy: focal brain lesions causing REM sleep behavior disorder. Sleep Med. 2009;10(1):9–12
  9. Mathis J, Hess CW, Bassetti C. Isolated mediotegmental lesion causing narcolepsy and rapid eye movement sleep behaviour disorder: a case evidencing a common pathway in narcolepsy and rapid eye movement sleep behaviour disorder. J Neurol Neurosurg Psychiatry. 2007;78:427–429
  10. Xi Z, Luning W. REM sleep behavior disorder in a patient with pontine stroke. Sleep Med. 2009;10(1):143–146
  11. Gómez-Choco MJ, Iranzo A, Blanco Y, Graus F, Santamaria J, Saiz A. Prevalence of restless legs syndrome and REM sleep behavior disorder in multiple sclerosis. Mult Scler. 2007;13:805–808
  12. Condurso R, rico I, Romanello G, Gervasi G, Silvestri R. Status dissociatus in multilacunar encephalopathy with median pontine lesion: a video-polygraphic presentation. J Sleep Res. 2006;15(Suppl. 1):212
  13. Provini F, Vetrugno R, Pastorelli F, et al. Status dissociatus after surgery for tegmental ponto-mesencephalic cavernoma: a state-dependent disorder of motor control during sleep. Mov Disord. 2004;19:719–723
  14. Lu J, Sherman D, Devor M, Saper CB. A putative flip-flop switch for control of REM sleep. Nature. 2006;441(7093):589–594
  15. Hans-Joachim Kretschmann, Wolfgang Weinrich. Cranial neuroimaging and clinical neuroanatomy. 3rd ed. revised and expanded. Stuttgart-New York: Thieme; 2004;p. 451
  16. Boeve BF, Silber MH, Ferman TJ. Melatonin for treatment of REM sleep behavior disorder in neurologic disorders: results in 14 patients. Sleep Med. 2003;4(4):281–284
  17. Jan JE, Feeman RD, Wasdell MB, Bomben MM. A child with severe night terrors and sleep-walking responds to melatonin therapy. Dev Med Child Neurol. 2004;46(11):789

PII: S1389-9457(09)00007-0

doi: 10.1016/j.sleep.2008.12.006

Sleep Medicine
Volume 10, Issue 9 , Pages 1059-1062 , October 2009

Article Tools

* Image Usage & Resolution