Sleep Medicine
Volume 10, Issue 1 , Pages 19-25 , January 2009

Hypnotic use for insomnia management in chronic obstructive pulmonary disease

  • Thomas Roth

      Affiliations

    • Corresponding Author InformationTel.: +1 313 876 2233; fax: +1 313 916 5150.

Received 11 March 2008 ,Revised 31 May 2008 ,Accepted 17 June 2008.

References 

  1. ATS S. Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 1995;152:S78–S119
  2. Watz H, Magnussen H. [Comorbidities of COPD]. Internist (Berl). 2006 Sep;47(9):895–896898–900
  3. Urbano F, Mohsenin V. Chronic obstructive pulmonary disease and sleep: the interaction. Panminerva Med. 2006;48(4):223–230
  4. Gay PC. Chronic obstructive pulmonary disease and sleep. Respir Care. 2004;49(1):39–51[discussion-2]
  5. Mermigkis CK, Foldvary-Schaefer N. Health-related quality of life in patients with obstructive sleep apnea and chronic obstructive pulmonary disease (overlap syndrome). Int J Clin Pract. 2007;61(2):207–211
  6. Fanfulla F, Cascone L, Taurino AE. Sleep disordered breathing in patients with chronic obstructive pulmonary disease. Minerva Med. 2004;95(4):307–321
  7. Fletcher ED, Midgren B, Zielinski J, Levi-Valensi P, Braghiroli A. Survival in COPD patients with a daytime PaO2 greater than 60mm Hg with and without nocturnal oxyhemoglobin desaturation. Chest. 1992;101(3):649–655
  8. George CF. Perspectives on the management of insomnia in patients with chronic respiratory disorders. Sleep. 2000;23(Suppl. 1):S31–S35[discussion S6–8]
  9. Borja NL, Daniel KL. Ramelteon for the treatment of insomnia. Clin Ther. 2006;28(10):1540–1555
  10. McCarley RM. Neurobiology of REM and NREM sleep. Sleep Med. 2007;8(4):302–330
  11. Berthon-Jones M, Sullivan CE. Ventilatory and arousal responses to hypoxia in sleeping humans. Am Rev Respir Dis. 1982;125(6):632–639
  12. Douglas NJ, White DP, Weil JV, Pickett CK, Zwillich CW. Hypercapnic ventilatory response in sleeping adults. Am Rev Respir Dis. 1982;126(5):758–762
  13. Douglas NJ, White DP, Pickett CK, Weil JV, Zwillich CW. Respiration during sleep in normal man. Thorax. 1982;37(11):840–844
  14. Douglas NJ. Sleep in patients with chronic obstructive pulmonary disease. Clin Chest Med. 1998;19(1):115–125
  15. Becker HF, Piper AJ, Flynn WE, McNamara SG, Grunstein RR, Peter JH, et al. Breathing during sleep in patients with nocturnal desaturation. Am J Respir Crit Care Med. 1999;159(1):112–118
  16. Ballard RD, Clover CW, Suh BY. Influence of sleep on respiratory function in emphysema. Am J Respir Crit Care Med. 1995;151(4):945–951
  17. Brown LK. Sleep-related disorders and chronic obstructive pulmonary disease. Respir Care Clin N Am. 1998;4(3):493–512
  18. Hudgel DW, Martin RJ, Johnson B, Hill P. Mechanics of the respiratory system and breathing pattern during sleep in normal humans. J Appl Physiol. 1984;56(1):133–137
  19. Mulloy E, McNicholas WT. Ventilation and gas exchange during sleep and exercise in severe COPD. Chest. 1996;109(2):387–394
  20. Chaouat A, Weitzenblum E, Krieger J, Ifoundza T, Oswald M, Kessler R. Association of chronic obstructive pulmonary disease and sleep apnea syndrome. Am J Respir Crit Care Med. 1995;151(1):82–86
  21. Bhullar S, Phillips B. Sleep in COPD patients. COPD. 2005;2(3):355–361
  22. Calderon-Osuna E, Carmona Bernal C, Arenas Gordillo M, Fuentes Pradera MA, Sanchez Armengol A, Capote Gil F. A comparative study of patients with chronic obstructive pulmonary disease with and without obstructive sleep apnea syndrome. Arch Bronconeumol. 1999;35(11):539–543
  23. Chaouat AW, Krieger J, Sforza E, Hammad H, Oswald M, Kessler R. Prognostic value of lung function and pulmonary haemodynamics in OSA patients treated with CPAP. Eur Respir J. 1999;13(5):1091–1096
  24. Douglas NJ. Chronic obstructive pulmonary disease. In:  Kryger MR,  Dement WC editor. Principles and practice of sleep medicine. 3rd ed.. Philadelphia: Saunders; 2000;p. 965–975
  25. Vallarino CR, Mini L. Prevalence of insomnia in patients with chronic obstructive pulmonary disease in a large database. Value Health. 2005;8(3):322
  26. Zhou YM, Wang XP, Zeng XY, Qiu R, Xie JF, Liu SM, et al. Theophylline in the treatment of chronic obstructive pulmonary disease: a randomized, double-blind, placebo-controlled study. Zhonghua Jie He He Hu Xi Za Zhi. 2006;29(9):577–582
  27. Zhou Y, Wang X, Zeng X, Qiu R, Xie J, Liu S, et al. Positive benefits of theophylline in a randomized, double-blind, parallel-group, placebo-controlled study of low-dose, slow-release theophylline in the treatment of COPD for 1 year. Respirology. 2006;11(5):603–610
  28. Gross NJ, Nelson HS, Lapidus RJ, Dunn L, Lynn L, Rinehart M, et al. Efficacy and safety of formoterol fumarate delivered by nebulization to COPD patients. Respir Med. 2008;102(2):189–197
  29. Guilleminault C, Silvestri R. Aging, drugs and sleep. Neurobiol Aging. 1982;3(4):379–386
  30. Fletcher EC, Levin DC. Cardiopulmonary hemodynamics during sleep in subjects with chronic obstructive pulmonary disease. The effect of short- and long-term oxygen. Chest. 1984;85(1):6–14
  31. Bain KT. Management of chronic insomnia in elderly persons. Am J Geriatr Pharmacother. 2006;4(2):168–192
  32. Ringdahl EN, Pereira SL, Delzell JE. Treatment of primary insomnia. J Am Board Fam Pract. 2004;17(3):212–219
  33. Ebert B, Wafford KA, Deacon S. Treating insomnia: Current and investigational pharmacological approaches. Pharmacol Ther. 2006;112(3):612–629
  34. Takeda. Prescribing information for ramelteon tablets. 2005 April 2006 [cited September 10, 2007]; Available from: www.rozerem.com/consumer/aboutrozerem_c2.aspx.
  35. Kryger M, Wang-Weigand S, Roth T. Safety of ramelteon in individuals with mild to moderate obstructive sleep apnea. Sleep Breath. 2007;11(3):159–164
  36. Conn DK, Madan R. Use of sleep-promoting medications in nursing home residents: risks versus benefits. Drugs Aging. 2006;23(4):271–287
  37. Jolly E, Aguirre L, Jorge E, Luna C. Acute effect of lorazepam on respiratory muscles in stable patients with chronic obstructive pulmonary disease. Medicina (B Aires). 1996;56(5 Pt. 1):472–478
  38. Cohn MA, Morris DD, Juan D. Effects of estazolam and flurazepam on cardiopulmonary function in patients with chronic obstructive pulmonary disease. Drug Saf. 1992;7(2):152–158
  39. Beaupre A, Soucy R, Phillips R, Bourgouin J. Respiratory center output following zopiclone or diazepam administration in patients with pulmonary disease. Respiration. 1988;54(4):235–240
  40. Berry RB, McCasland CR, Light RW. The effect of triazolam on the arousal response to airway occlusion during sleep in normal subjects. Am Rev Respir Dis. 1992;146(5 Pt. 1):1256–1260
  41. Berry RK, Bower J. Triazoloam in patients with obstructive sleep apnea. Am J Respir Crit Care Med. 1995;151(2):450–454
  42. Hayashi T, Nakamura S, Ohno R, Kusumoto G, Terayama K, Murakami Y, et al. How do diazepam and flumazenil influence respiratory control by the activities of both hypoglossal and phrenic nerves in rabbits?. Masui. 2003;52(12):1286–1292
  43. Nishino T, Shirahata M, Yonezawa T, Honda Y. Comparison of changes in the hypoglossal and the phrenic nerve activity in response to increasing depth of anesthesia in cats. Anesthesiology. 1984;60(1):19–24
  44. Yamakage M, Matsuzaki T, Tsujiguchi N, Honma Y, Namiki A. Inhibitory effects of diazepam and midazolam on Ca2+ and K+ channels in canine tracheal smooth muscle cells. Anesthesiology. 1999;90(1):197–207
  45. Sanger DJ. The pharmacology and mechanisms of action of new generation, non-benzodiazepine hypnotic agents. CNS Drugs. 2004;18(Suppl. 1):9–15[discussion 41, 3–5]
  46. Ranlov PJ, Nielsen SP. Effect of zopiclone and diazepam on ventilatory response in normal human subjects. Sleep. 1987;10(Suppl. 1):40–47
  47. Girault C, Muir JF, Mihaltan F, Borderies P, De La Giclais B, Verdure A, et al. Effects of repeated administration of zolpidem on sleep, diurnal and nocturnal respiratory function, vigilance, and physical performance in patients with COPD. Chest. 1996;110(5):1203–1211
  48. Cohn MA. Effects of zolpidem, codeine phosphate and placebo on respiration. A double-blind, crossover study in volunteers. Drug Saf. 1993;9(4):312–319
  49. Muir JF, DeFouilloy C, Broussier P, Locquet R, Maillard F. Comparative study of the effects of zopiclone and placebo on respiratory function in patients with chronic obstructive respiratory insufficiency. Int Clin Psychopharmacol. 1990;5(Suppl. 2):85–94
  50. Glass J, Lanctot KL, Herrmann N, Sproule BA, Busto UE. Sedative hypnotics in older people with insomnia: meta-analysis of risks and benefits. BMJ. 2005;331(7526):1169
  51. Antonelli-Incalzi R, Corsonello A, Trojano L, Pedone C, Acanfora D, Spada A, et al. Screening of cognitive impairment in chronic obstructive pulmonary disease. Dement Geriatr Cogn Disord. 2007;23(4):264–270
  52. Kato KH, Nishiyama K, Uchikawa O, Fukatsu K, Ohkawa S, Kawamata Y, et al. Neurochemical properties of ramelteon (TAK-375), a selective MT1/MT2 receptor agonist. Neuropharmacology. 2005;48(2):301–310
  53. Fisher SP, Davidson K, Kulla A, Sugden D. Acute sleep-promoting action of the melatonin agonist, ramelteon, in the rat. J Pineal Res. 2008;19
  54. Erman M, Seiden D, Zammit G, Sainati S, Zhang J. An efficacy, safety, and dose–response study of ramelteon in patients with chronic primary insomnia. Sleep Med. 2006;7(1):17–24
  55. Roth TS, Wang-Weigand S, Zhang J. A 2-night, 3-period, crossover study of ramelteon’s efficacy and safety in older adults with chronic insomnia. Curr Med Res Opin. 2007;23(5):1005–1014
  56. Kryger M, Roth T. Ramelteon does not exacerbate respiratory depressant effects in patients with moderate to severe COPD. Proceedings of the 53rd international respiratory congress of the American Association for respiratory care. 2007. December 2007;
  57. Luparini MR, Garrone B, Pazzagli M, Pinza M, Pepeu G. A cortical GABA-5HT interaction in the mechanism of action of the antidepressant trazodone. Prog Neuropsychopharmacol Biol Psychiatry. 2004;28(7):1117–1127
  58. James SP, Mendelson WB. The use of trazodone as a hypnotic: a critical review. J Clin Psychiatry. 2004;65(6):752–755
  59. Mendelson WB. A review of the evidence for the efficacy and safety of trazodone in insomnia. J Clin Psychiatry. 2005;66(4):469–476
  60. Stradling JR, Chadwick GA, Frew AJ. Changes in ventilation and its components in normal subjects during sleep. Thorax. 1985;40(5):364–370
  61. Fletcher EC, Luckett RA, Miller T, Costarangos C, Kutka N, Fletcher JG. Pulmonary vascular hemodynamics in chronic lung disease patients with and without oxyhemoglobin desaturation during sleep. Chest. 1989;95(4):757–764
  62. Griffiths RR, Johnson MW. Relative abuse liability of hypnotic drugs: a conceptual framework and algorithm for differentiating among compounds. J Clin Psychiatry. 2005;66(Suppl. 9):31–41
  63. Tsai MJ, Tsai YH, Huang YB. Compulsive activity and anterograde amnesia after zolpidem use. Clin Toxicol (Phila). 2007;45(2):179–181

PII: S1389-9457(08)00164-0

doi: 10.1016/j.sleep.2008.06.005

Sleep Medicine
Volume 10, Issue 1 , Pages 19-25 , January 2009

Article Tools