Sleep Medicine
Volume 10, Issue 3 , Pages 368-373 , March 2009

Cardiorespiratory response to exercise in men and women with obstructive sleep apnea

Received 17 August 2007 ,Revised 18 April 2008 ,Accepted 26 April 2008.

References 

  1. Nieto FJ, Young TB, Lind BK, Shahar E, Samet JM, Redline S, et al. Association of sleep-disordered breathing, sleep apnea, and hypertension in a large community-based study. Sleep Heart Health Study. JAMA. 2000;283(14):1829–1836
  2. Peppard PE, Young T, Palta M, Skatrud J. Prospective study of the association between sleep-disordered breathing and hypertension. N Engl J Med. 2000;342(19):1378–1384
  3. Shahar E, Whitney CW, Redline S, Lee ET, Newman AB, Javier Nieto F, et al. Sleep-disordered breathing and cardiovascular disease: cross-sectional results of the Sleep Heart Health Study. Am J Respir Crit Care Med. 2001;163(1):19–25
  4. Dziewas R, Humpert M, Hopmann B, Kloska S, Ludemann P, Ritter M, et al. Increased prevalence of sleep apnea in patients with recurring ischemic stroke compared with first stroke victims. J Neurol. 2005;252(11):1394–1398
  5. Marin JM, Carrizo SJ, Vicente E, Agusti AGN. Long-term cardiovascular outcomes in men with obstructive sleep apnea–hypopnoea with or without treatment with continuous positive airway pressure: an observational study. Lancet. 2005;365:1046–1053
  6. Cavell RM. The exercise treadmill test for diagnosis and prognosis of coronary artery disease. J La State Med Soc. 1995;147(5):197–201
  7. Haraphongse M, Senaratne M, Steljes A, Kappagoda T, Rossall RE. Incremental value of the exercise treadmill test in determining the extent of coronary artery disease: a discriminant function analysis. Clin Invest Med. 1985;8(3):214–221
  8. Antunes E, Galrinho A, Ferreira R, Catarino C, Serra J, de Oliveira M, et al. Functional significance of premature ventricular complex morphology evaluated during treadmill exercise stress test in patients with coronary artery disease. Rev Port Cardiol. 1992;11(11):923–926
  9. Peppard PE, Young T. Exercise and sleep-disordered breathing: an association independent of body habitus. Sleep. 2004;27(3):480–484
  10. Guillermo LQ, Gal TJ, Mair EA. Does obstructive sleep apnea affect aerobic fitness?. Ann Otol Rhinol Laryngol. 2006;115(10):715–720
  11. Lin CC, Hsieh WY, Chou CS, Liaw SF. Cardiopulmonary exercise testing in obstructive sleep apnea syndrome. Respir Physiol Neurobiol. 2006;150(1):27–34
  12. Schlosser BM, Walther JW, Rasche K, Bauer TT, Orth M, de Zeeuw J, et al. Improvement of cardiopulmonary exercise capacity in patients with obstructive sleep apnea syndrome under CPAP therapy. Med Klin (Munich) 2006;101(2):107–13.
  13. Przybylowski T, Bielicki P, Kumor M, Hildebrand K, Maskey-Warzechowska M, Wiwala J, et al. Influence of nasal continuous positive airway pressure on response to exercise in patients with obstructive sleep apnea syndrome. Pneumonol Alergol Pol. 2006;74(1):39–44
  14. Duchna HW, Hauptmeier B, Orth M, Schultze-Werninghaus G, Schäfer. Daytime ventilatory efficiency in obstructive sleep apnea syndrome – influence of CPAP-therapy. Pneumologie 2007 [Epub ahead of print].
  15. Rechtschaffen A, Kales A. A manual of standardized terminology, technique and scoring system for sleep stages of human sleep. Los Angeles, CA: Los Angeles Brain Information Service, Brain Information Institute; 1968.
  16. EEG arousals: scoring rules and examples. A preliminary report from Sleep Disorders Atlas Task Force of the American Sleep Disorders Association. Sleep 1992;15:173–84.
  17. Sleep-Related Breathing Disorders in Adults: Recommendations for syndrome definition and measurement techniques in clinical research. The report of an American Academy of Sleep Medicine Task Force. Sleep 1999;22: 667–89.
  18. Standardization of Spirometry, 1994 Update. American Thoracic Society. Am J Respir Crit Care Med 1995;152(3):1107–36.
  19. Barbosa e Silva O, Filho DCS. Uma nova proposta para orientar a velocidade de inclinação no protocolo em rampa na esteira ergométrica. Arq Bras Cardiol. 2003;81(1):42–47
  20. Borg G. Ratings of perceived exertion and heart rates during short-term cycle exercise and their use in a new cycling strength test. Int J Sports Med. 1982;3(3):153–158
  21. Javaheri S, Parker TJ, Liming JD, Corbett WS, Nishiyaua H, Wexler L, et al. Sleep apnea in 81 ambulatory male patients with stable heart failure: types and their prevalences, consequences, and presentations. Circulation. 1998;97:2154–2159
  22. Miller WP. Cardiac arrhythmias and conduction disturbances in the sleep apnea syndrome. Prevalence and significance. Am J Med. 1982;73:317–321
  23. Guilleminault C, Connoly SJ, Winkle RA. Cardiac arrhythmias and conduction disturbances during sleep in 400 patients with sleep apnea syndrome. Am J Cardiol. 1983;52:490–494
  24. Alam I, Lewis K, Stephens JW, et al. Obesity, metabolic syndrome and sleep apnoea: all pro-inflammatory states. Obes Rev. 2007;8(2):119–127
  25. Bassetti CL. Sleep and stroke. Semin Neurol. 2005;52(1):19–32
  26. Alonso-Fernãndez A, García-Río F, Arias MA, Mediano O, Pino JM, Martínez I, et al. Obstructive sleep apnoea–hypoapnoea syndrome reversibly depresses cardiac response to exercise. Eur Heart J. 2006;27(2):207–215
  27. Jordan AS, Wellman A, Edwards JK, Schory K, Dover L, MacDonald M, et al. Respiratory control stability and upper airway collapsibility in men and women with obstructive sleep apnea. J Appl Physiol. 2005;99(5):2020–2027
  28. Pillar G, Malhotra A, Fogel R, Beauregard J, Schnall R, White DP. Airway mechanics and ventilation in response to resistive loading during sleep: influence of gender. Am J Respir Crit Care Med. 2000;162(5):1627–1632
  29. Vincent HK, Shanely RA, Stewart DJ, Demirel HA, Hamilton KL, Ray AD, et al. Adaptation of upper airway muscles to chronic endurance exercise. Am J Respir Crit Care Med. 2002;166(3):287–293
  30. Melissant CF, Lammers JW, Demedts M. Relationship between external resistances, lung function changes and maximal exercise capacity. Eur Respir J. 1998;11(6):1369–1375
  31. Venables MC, Achten J, Jeukendrup AE. Determinants of fat oxidation during exercise in healthy men and women: a cross-sectional study. J Appl Physiol. 2005;98(1):160–167
  32. Shepertycky MR, Banno K, Kryger MH. Differences between men and women in the clinical presentation of patients diagnosed with obstructive sleep apnea syndrome. Sleep. 2005;28(3):309–314

PII: S1389-9457(08)00107-X

doi: 10.1016/j.sleep.2008.04.006

Sleep Medicine
Volume 10, Issue 3 , Pages 368-373 , March 2009