Sleep Medicine
Volume 7, Issue 6 , Pages 513-520 , September 2006

Chronic fatigue, unrefreshing sleep and nocturnal polysomnography

  • Christian Guilleminault

      Affiliations

    • Stanford University Sleep Disorders Clinic, 401 Quarry road, suite 3301, Stanford, CA 94305, USA
    • Corresponding Author InformationCorresponding author. Tel.: +1 650 723 6601; fax: +1 650 725 89 10.
    • ,
  • Dalva Poyares

      Affiliations

    • Stanford University Sleep Disorders Clinic, 401 Quarry road, suite 3301, Stanford, CA 94305, USA
    • Department of Psychobiology, Sleep Institute, Federal University of Sao Paulo, Sao Paulo, Brazil
    • ,
  • Agostinho da Rosa

      Affiliations

    • Department of Psychobiology, Sleep Institute, Federal University of Sao Paulo, Sao Paulo, Brazil
    • ,
  • Ceyda Kirisoglu

      Affiliations

    • Stanford University Sleep Disorders Clinic, 401 Quarry road, suite 3301, Stanford, CA 94305, USA
    • ,
  • Tatiana Almeida

      Affiliations

    • Department of Psychobiology, Sleep Institute, Federal University of Sao Paulo, Sao Paulo, Brazil
    • ,
  • Maria Cecilia Lopes

      Affiliations

    • Stanford University Sleep Disorders Clinic, 401 Quarry road, suite 3301, Stanford, CA 94305, USA

Received 2 January 2006 ,Revised 28 February 2006 ,Accepted 6 March 2006.

References 

  1. Evengard B, Klimas N. Chronic Fatigue Syndrome: probable pathogenesis and possible treatments. Drugs. 2002;62:2433–2446
  2. Reynolds KJ, Vernon SD, Bouchery E, Reeves WC. The economic impact of chronic fatigue syndrome. Cost Eff Resour Alloc. 2004;2:4
  3. Nisenbaum R, Jones JF, Unger ER, et al. A population-based study of the clinical course of chronic fatigue syndrome. Health Qual Life Outcomes. 2003;03:1–49
  4. Nisenbaum R, Reyes M, Unger ER, Reeves WC. Factor analysis of symptoms among subjects with unexplained chronic fatigue: what can we learn about chronic fatigue syndrome?. J Psychosom Res. 2004;56:171–178
  5. Jason LA, Holbert C, Torres-Harding S, et al. Chronic fatigue syndrome versus neuroendocrineimmune dysfunction syndrome: differential attributions. J Health Soc Policy. 2003;18:43–55
  6. Papanicolaou DA, Amsterdam JD, Levine S, et al. Neuroendocrine aspects of chronic fatigue syndrome. Neuroimmunomodulation. 2004;11:65–74
  7. Skowera A, Cleare A, Blair D, et al. High levels of type 2 cytokine-producing cells in chronic fatigue syndrome. Clin Exp Immunol. 2004;135:294–302
  8. Staines DR. Is chronic fatigue syndrome an autoimmune disorder of endogenous neuropeptides, exogenous infection and molecular mimicry?. Med Hypotheses. 2004;2:646–652
  9. Busichio K, Tiersky LA, Deluca J, Natelson BH. Neuropsychological deficits in patients with chronic fatigue syndrome. J Int Neuropsychol Soc. 2004;10:278–285
  10. De Lange FP, Kalkman JS, Bleijenberg G, et al. Neural correlates of the chronic fatigue syndrome–an fMRI study. Brain 2004;127:1948–1957.
  11. Richards RS, Roberts TK, McGregor NR, et al. Blood parameters indicative of oxidative stress are associated with symptom expression in chronic fatigue syndrome. Redox Rep. 2000;5:35–41
  12. Cleare AJ. The HPA axis and the genesis of chronic fatigue syndrome. Trends Endocrinol Metab. 2004;15:55–59
  13. Crofford LJ, Young EA, Engleberg NC, et al. Basal circadian and pulsatile ACTH and cortisol secretion in patients with fibromyalgia and/or chronic fatigue syndrome. Brain Behav Immun. 2004;18:314–325
  14. Unger ER, Nisenbaum R, Moldofsky H, et al. Sleep assessment in a population-based study of chronic fatigue syndrome. BMC Neurol. 2004;4:6
  15. Fischler B. Review of clinical and psycholobiological dimensions of the chronic fatigue syndrome: differentiatation from depression and contribution to sleep dysfunctions. Sleep Med Rev. 1999;3:133–146
  16. Moldofsky H. Non-restorative sleep and symptoms after a febrile illness in patients with fibrositis and chronic fatigue syndrome. J Rheumatol. 1989;16:150–153
  17. Whelton CL, Salit I, Moldofsky H. Sleep, Epstein-Barr virus infection, musculoskeletal pain, and depressive symptoms in chronic fatigue syndrome. J Rheumatol. 1992;19:939–943
  18. Manu P, Lane TJ, Matthews DA, et al. Alpha–delta sleep in patients with a chief complaint of chronic fatigue. South Med J. 1994;87:465–470
  19. Mahowald ML, Mahowald MW. Nighttime and daytime functioning (sleepiness and fatigue) in less well-defined chronic rheumatic diseases with particular reference to the ‘alpha–delta NREM sleep anomaly’. Sleep Med. 2000;1:195–207
  20. Mahowald MW, Mahowald ML, Bundlie SR, Ytterberg SR. Sleep fragmentation in rheumatoid arthritis. Arthritis Rheum. 1989;32:974–983
  21. Flanigan MJ, Morehouse RL, Shapiro CM. Determination of observer-rated alpha activity during sleep. Sleep. 1995;18:702–706
  22. Zubieta JK, Demitrack MA, Shipley JE, et al. in chronic fatigue syndrome: comparison with major depression. Biol Psychiatry. 1993;33:73A–74A
  23. Johns MW. A new method for measuring daytime sleepiness: the Epworth sleepiness scale. Sleep. 1991;14:540–545
  24. Krupp LB, LaRocca NG, Muir-Nash J, Steinberg AD. The fatigue severity scale. Application to patients with multiple sclerosis and systemic lupus erythematosus. Arch Neurol. 1989;46:1121–1123
  25. Morriss RK, Wearden AJ, Battersby L. The relationship of sleep difficulties to fatigue, mood and disability in chronic fatigue syndrome. J Psychosom Res. 1997;42:597–605
  26. Rechtschaffen A, Kales A. A Manual of standardized terminology, technique and scoring system for sleep stages of human sleep. Los Angeles, CA: Los Angeles Brain Information Service, Brain Information Institute; 1968;
  27. American Sleep Disorders Association. EEG arousals: scoring rules and examples. A preliminary report from Sleep Disorders Atlas Task Force of the American Sleep Disorders Association. Sleep. 1992;15:173–184
  28. American Academy of Sleep Medicine. Sleep-Related Breathing Disorders in Adults: Recommendations for syndrome definition and measurement techniques in clinical research. The report of an American Academy of Sleep Medicine Task Force. Sleep. 1999;22:667–689
  29. Guilleminault C, Poyares D, Palombini L, et al. Variability of respiratory effort in relationship with sleep stages in normal controls and Upper Airway Resistance Syndrome patients. Sleep Med. 2001;2:397–406
  30. Rosa AC, Parrino L, Terzano MG. Automatic detection of cyclic alternating pattern (CAP) sequences in sleep: preliminary results. Clin Neurophysiol. 1999;110(4):585–592
  31. Terzano MG, Parrino L, Boselli M, et al. Polysomnographic analysis of arousal responses in obstrutive sleep apnea syndrome by means of the cyclic alternating pattern. Clin Neurophysiol. 1996;13:145–155
  32. Terzano MG, Parrino L, Sherieri A, et al. Atlas, rules, and recording techniques for the scoring of cyclic alternating pattern (CAP) in human sleep. Sleep Med. 2002;3:187–199
  33. Terzano MG, Parrino L, Spaggiari MC. CAP variables and arousals as sleep electroencephalogram markers for primary insomnia. Clin Neurophysiol. 2003;114:1715–1723
  34. Sharpley A, Clements A, Hawton K, Sharpe M. Do patients with ‘pure’ chronic fatigue syndrome (neurasthenia) have abnormal sleep?. Psychosom Med. 1997;59:592–596
  35. Fischler B, Le Bon O, Hoffmann G, et al. Sleep anomalies in the chronic fatigue syndrome. Neuropsychobiology. 1997;35:115–122
  36. Ball N, Buchwald D, Schmidt D, et al. Monozygotic twins discordant for chronic fatigue syndrome. Objective measures of sleep. J Psychosom Res. 2004;56:207–212
  37. Zucconi M, Oldani A, Ferrini-Strambi L, Smirne S. Arousal fluctuations in non-rapid eye movement parassomnias: the role of cyclic alternating pattern as a measure of arousal instability. J Clin Neurophysiol. 1995;12:147–154
  38. Gillberg M, Akerstedt T. Sleep restriction and SWS-suppression: effects on daytime alertness and night-time recovery. J Sleep Res. 1994;3:144–151
  39. Guilleminault Lee JH, Chan A, Lopes MC, et al. Non-REM-sleep instability in recurrent sleepwalking in pre-pubertal children. Sleep Med. 2005;
  40. Guilleminault C, Kirisoglu C, Bao G, et al. Adult chronic sleepwalking and its treatment based on polysomnography. Brain. 2005;128:1062–1069
  41. Lopes MC, Rosa A, Roizenblatt S, et al. Cyclic alternating pattern in peripubertal Children. Sleep. 2005;28:215–219
  42. Guilleminault C, Kirisoglu C, Rosa A da, et al. Sleepwalking, a disorder of NREM sleep instability. Sleep Med 2006;7:163–170.
  43. Schenck CH, Pareja JA, Patterson AL, Mahowald MW. Analysis of polysomnographic events suroundind 252 slow wave sleep arousals in 38 adults with injurious sleepwalking and sleep terrors. J Clin Neurophysiol. 1998;15:159–166
  44. Pressman MR. Hypersynchronous delta sleep EEG activity and sudden arousal from slow-wave sleep in adults without a history of parasomnia: clinical and forensic implication. Sleep. 2004;27:706–710
  45. Bao G, Guilleminault C. Upper airway resistance syndrome 1 decade later. Curr Opin Pulm Med. 2004;10:461–467
  46. Chervin RD, Burns JW, Subotic NS, et al. Correlates of respiratory cycle-related EEG changes in children with sleep-disordered breathing. Sleep. 2004;27:116–122
  47. Chervin RD, Burns JW, Ruzicka DL. Electroencephalographic changes during respiratory cycles predict sleepiness in sleep apnea. Am J Respir Crit Care Med. 2005;171:652–658
  48. Guilleminault C, Huang YS, Kirisoglu C, Chan A. Is OSAS a neurologic disorder? A CPAP follow-up study. Ann Neurol. 2005;58:880–887
  49. Lentz MJ, Landis CA, Rothermel J, Shaver JL. Effects of selective slow wave sleep disruption on musculoskeletal pain and fatigue in middle aged women. J Rheumatol. 1999;26:1586–1592
  50. Vergara JM, Brualla J, Serrano M, et al. Subjective sleep quality and spectral analysis of electroencephalography during nocturnal sleep. Rev Neurol (Paris). 1999;152:765–767

PII: S1389-9457(06)00107-9

doi: 10.1016/j.sleep.2006.03.016

Sleep Medicine
Volume 7, Issue 6 , Pages 513-520 , September 2006

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