Sleep Medicine
Volume 7, Issue 5 , Pages 407-417 , August 2006

Efficacy and safety of pramipexole in idiopathic restless legs syndrome: A polysomnographic dose-finding study—The PRELUDE study

  • Markku Partinen

      Affiliations

    • Skogby Sleep Clinic, Rinnekoti Research Centre, Kumputie 3, FI-02980 Espoo, Finland
    • Department of Neurology, University of Helsinki, FI-00014 Helsinki, Finland
    • Corresponding Author InformationCorresponding author. Address: Skogby Sleep Clinic, Rinnekoti Research Centre, Kumputie 3, FI-02980 Espoo, Finland. Tel.:+358 9 8551345; fax: +358 9 8551375.
    • Dr Partinen has received a grant from the Rinnekoti Research Foundation for his studies on restless legs syndrome (RLS), and he has received honoraria, totaling less than USD10,000per year, for his presentations in postgraduate symposia on RLS.
    • ,
  • Kari Hirvonen

      Affiliations

    • Skogby Sleep Clinic, Rinnekoti Research Centre, Kumputie 3, FI-02980 Espoo, Finland
    • Neurotest Tampere Oy, Hatanpään Valtatie 1, FIN-33100 Tampere, Finland
    • The author has no conflict of interest related to this article.
    • ,
  • Leni Jama

      Affiliations

    • Skogby Sleep Clinic, Rinnekoti Research Centre, Kumputie 3, FI-02980 Espoo, Finland
    • The author has no conflict of interest related to this article.
    • ,
  • Anniina Alakuijala

      Affiliations

    • Skogby Sleep Clinic, Rinnekoti Research Centre, Kumputie 3, FI-02980 Espoo, Finland
    • Department of Clinical Neurophysiology, University Hospital of Helsinki, P.O. Box 340, FI-00029 Helsinki, Finland
    • The author has no conflict of interest related to this article.
    • ,
  • Christer Hublin

      Affiliations

    • Finnish Institute of Occupational Health, Brain at Work Research Center, Topeliuksenkatu 41 a A, FI-00250 Helsinki, Finland
    • Department of Neurology, University of Helsinki, FI-00014 Helsinki, Finland
    • The author has no conflict of interest related to this article.
    • ,
  • Ilkka Tamminen

      Affiliations

    • Medical Division, Boehringer Ingelheim Finland Ky, Tammasaarenkatu 5, FI-00180 Helsinki, Finland
    • The author has no conflict of interest related to this article.
    • ,
  • Juergen Koester

      Affiliations

    • Medical Division, Boehringer Ingelheim International GmbH, Binger Str. 173, 55216 Ingelheim, Germany
    • The author has no conflict of interest related to this article.
    • ,
  • Juergen Reess

      Affiliations

    • Department of Clinical Research CNS, Boehringer Ingelheim Pharma GmbH and Co. KG, Birkendorferstr.65, 88397 Biberach, Germany
    • The author has no conflict of interest related to this article.

Received 22 November 2005 ,Revised 16 February 2006 ,Accepted 6 March 2006.

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☆ PRELUDE, Pramipexole for RLS: efficacy and tolerability of the usage of dopamine agonists.

PII: S1389-9457(06)00100-6

doi: 10.1016/j.sleep.2006.03.011

Sleep Medicine
Volume 7, Issue 5 , Pages 407-417 , August 2006

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