Sleep Medicine
Volume 2, Issue 2 , Pages 145-151 , March 2001

Effects of short-term PAP treatment on endurance exercise performance in obstructive sleep apnea patients

  • D Edward Shifflett Jr

      Affiliations

    • Laboratory for Health and; Exercise Sciences, 230 War Memorial Hall, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA
  • ,
  • Eric W Walker

      Affiliations

    • Laboratory for Health and; Exercise Sciences, 230 War Memorial Hall, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA
  • ,
  • John M Gregg

      Affiliations

    • Department of Biomedical Sciences and Pathobiology, Virginia-Maryland Regional College of Veterinary Medicine, Blacksburg, VA 24061, USA
  • ,
  • Don Zedalis

      Affiliations

    • Sleep Disorders Network of Southwest Virginia, 2955 Market Street, Christiansburg, VA, USA 24073
  • ,
  • William G Herbert

      Affiliations

    • Laboratory for Health and; Exercise Sciences, 213 War Memorial Hall, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA
    • Corresponding Author InformationCorresponding author. Tel.: +1-540-231-6565; fax: +1-540-231-8476

Received 24 February 2000 ,Revised 25 July 2000 ,Accepted 29 August 2000.

References 

  1. Systematic review of the literature regarding the diagnosis of sleep apnea. Summary, evidence report/technology assessment: number 1, December 1998. Agency for Health Care Policy and Research, Rockville, MD. (http://www.ahcpr.gov/clinic/apnea.htm)
  2. Young T, Palta M, Dempsey J, Skatrud J, et al.  The occurrence of sleep disordered breathing among middle aged adults. N Engl J Med. 1993;328:1230–1235
  3. Mooe T, Rabben T, Woklund U, Franklin K, et al.  Sleep disordered breathing in men with coronary artery disease. Chest. 1996;109:659–663
  4. Mooe T, Rabben T, Wiklund U, Franklin K, et al.  Sleep disordered breathing in women: occurrence and association with coronary artery disease. Am J Med. 1996;101:251–256
  5. Hung J, Whitford E, Parsons R, Hillman D. Association of sleep apnea with myocardial infarction in men. Lancet. 1990;336:261–264
  6. Mayer J, Becker H, Brandenburg U, Penzel T, et al.  Blood pressure and sleep apnea: results of long term nasal continuous positive airway pressure therapy. Cardiology. 1991;79:84–92
  7. Stradling J, Davies R. Obstructive sleep apnea. Evidence for efficacy of continuous positive airways pressure is compelling. Br Med J. 1997;315:368
  8. Konermann M, Sanner B, Klewer J, Kreuzer I, et al.  Modification of cardiopulmonary parameters in patients with obstructive sleep apnea treated with nCPAP therapy. Wien. Med. Wochenschr. 1996;146:340–343
  9. Taguchi O, Hida W, Okabe S, Ebihara S, et al.  Improvement of exercise performance with short-term nasal continuous positive airway pressure in patients with obstructive sleep apnea. Tokohu J Exp Med. 1997;183:45–53
  10. Hawrylkiewicz I, Cieslicki J, Palasiewicz G, Koziej M, et al.  Pulmonary circulation at rest and during exercise in patients with obstructive sleep apnea before and after one year of treatment with CPAP. Pneumonol Alergol Pol. 1996;64(9–10):638–643
  11. Levy P, Guilleminault C, Fagret D, Gaio J, et al.  Changes in left ventricular ejection fraction during REM sleep and exercise in chronic obstructive pulmonary disease and sleep apnoea syndrome. Eur Respir J. 1991;4(3):347–352
  12. Netzer N, Lormes W, Giebelhaus V, Halle M, et al.  Physical training of patients with sleep apnea. Pneumologie. 1997;51(Suppl 3):779–782
  13. Vanuxem D, Badier M, Guillot C, Delpierre S, et al.  Impairment of muscle energy metabolism in patients with sleep apnoea syndrome. Respir. Med. 1997;91(9):551–557
  14. Schonhofer B, Rosenbluh J, Voshaar T, Kohler D. Ergometry separates sleep apnea syndrome from obesity-hypoventilation after positive pressure ventilation therapy. Pneumologie. 1997;51(12):1115–1119
  15. In:  Rechtschaffen A,  Kales A editor. A manual of standardized terminology, techniques and scoring system for sleep stages of human subjects. Bethesda, MD: National Institute of Neurological Disease and Blindness; 1968;NIH publication no. 204
  16. Anonymous . EEG arousals-scoring rules and examples- A preliminary report from the Sleep Disorders Atlas Task Force of the American Sleep Disorders Association. Sleep. 1992;15(2):174–184
  17. Borg G. Psychophysical scaling with applications in physical work and the perception of exertion. Scand J Work Environ Health. 1990;16(Suppl 1):55–58
  18. Rowell L. Human circulation: regulation during physical stress. New York: Oxford Press; 1986;
  19. Somers V, Dyken M, Clary M, Abboud F. Sympathetic neural mechanisms in obstructive sleep apnea. J Clin Invest. 1995;96(4):1897–1904
  20. Narkiewicz K, Montano N, Cogliati C, van de Borne P, et al.  Altered cardiovascular variability in obstructive sleep apnea. Circulation. 1998;98(11):1071–1077
  21. Hedner J, Ejnell H, Sellgren J, Hedner T. Is high and fluctuating muscle nerve sympathetic activity in the sleep apnea syndrome of pathogenetic importance for the development of hypertension?. J Hypertens. 1988;6:S529–S531
  22. Carlson J, Hender J, Elam M, Ejnell H. Augmented resting sympathetic activity in awake patients with obstructive sleep apnea. Chest. 1993;103:1763–1768
  23. Engleman H, Kingshott R, Wraith P, Mackay T, et al.  Randomized placebo-controlled crossover trial of continuous positive airway pressure for mild sleep apnea/hypopnea syndrome. Am J Respir Crit Care Med. 1999;159(2):461–467

PII: S1389-9457(00)00070-8

Sleep Medicine
Volume 2, Issue 2 , Pages 145-151 , March 2001